View Autoimmune Hemolytic Anemia Diagnosis UK. It should be part of the differential diagnosis for any normocytic or macrocytic anemia. Autoimmune hemolytic anemia is an uncommon group of disorders that can occur at any age.
These disorders affect women more often than men.
The direct antiglobulin (direct coombs) test establishes the diagnosis and may suggest the cause. Paroxysmal nocturnal hemoglobinuria is a disorder characterized by a decrease of red blood cells (anemia). An autoimmune disorder, such as rheumatoid arthritis or lupus. It happens when the body produces antibodies that destroy the red blood cells.
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